Introduction: in Cuba there are very few morphofunctional studies of placentas from twin pregnancies that allow establishing a general morphometric pattern. Implementing these informational databases would help to improve the actions of the National Sexual and Reproductive Health Program in the country. Objective: to systematize information on morphometric studies in twin placentas to build the epistemic basis for the characterization of the morphometric pattern of twin placentas and its relationship with chorionicity, the function of this organ and the degree of fetal and neonatal well-being. Method: a search strategy was applied in the period January 2020 to April 2021, in international databases (Medline, EMBASE, LILACS, Scopus, Google Scholar) for the bibliographic review, using the analysis and criticism method. of the sources from the content analysis procedure. An algorithm was used to make decisions about relevance, news, news and contributions. Results: 16 bibliographic sources were found on the research topic, among them: only one thesis (6.25%) and 4 edited texts (25.0%). Scientific articles (68.75%) from the last five years (93.75%) predominated. All the sources contributed to the construction of the theoretical referents. Conclusions: the morphometric study of the placenta in twin pregnancies is an insufficiently developed area in the knowledge of basic biomedical sciences, given the scarce bibliographic production on the subject.

Introduction: multiorgan dysfunction syndrome is characterized by the development of a progressive and potentially reversible physiological dysfunction in two or more organs induced by a wide variety of aggresive situations. The immune-inflammatory system plays an indispensable role in its pathogenesis. Objective: to identify the mortality-associated factors in patients with multiorgan dysfunction syndrome. Method: an analytical, observational, and retrospective cohort study was developed in 68 patients with multiorgan dysfunction syndrome attended in the Intensive Care Medicine Service at the Hospital General Docente "Abel Santamaría Cuadrado", Pinar del Río, between 2018 and 2019. Variables used: age, sex, diagnosis at admission, nutritional assessment, score accordind to Sequential Organ Failure Assessment (SOFA), complications arose, systems and number of organs in failing process. Results: male patients (60.3%) and age group between 60 and 79 (47.06%) were predominant. There was statistically significant association (p<0.05) between SOFA score and the number of failing organs at discharge. Respiratory complications were reported in 36% of deceased patients and in 38.89% of those discharged alive. Patients with cardiovascular failure were the most common (77.94%). Respiratory failure (p<0.001, OR:9 CI:2.52-32.08) and SOFA = 16 (p<0.042, OR:8.76 CI:1.07-71.51) increased the risk of decease-related discharge. Conclusions: excessive body mass index and obesity, admission shock, high score of SOFA, respiratory and nerveous failure, as well as the enormeus failure of organs were associated with the worsen prognoses and with the highest probability of decease.

Introduction: more than 40% of the population has a variable risk of contracting malaria in countries where its transmission persists, which constitutes a major global health problem. Objective: to identify the clinical characteristics, evolution and treatment of children with neurological disorders caused by Plasmodium falciparum as forms of malaria. Method: an observational, descriptive study of a series of cases was carried out in a random sample of 30 patients, who were admitted to the Clinic “Dr. Loeri Comba”, in Equatorial Guinea, with a diagnosis of malaria caused by this protozoan, and with associated neurological alterations, during the period from June 2017 to September 2019. Results: seizure (33.3%) and coma (30%) were the most frequent clinical forms, especially in those under four years of age. High parasitaemia was not present in all of them, although it predominated in the 63.3%. The response to treatment with intravenous artesunate as the drug of choice was favorable (90%), also incorporating vitamins at high doses in complex form, zinc sulfate, anticonvulsants, dexamethasone and mannitol, creating a treatment protocol of its own in the Pediatric service. There were three deaths from respiratory infection, caused by the type of pneumonia associated with malaria. Conclusions: children with neurological alterations caused by Plasmodium falciparum in malaria are not only evidenced in the coma state that causes the disease, but also in other forms of presentation with impaired consciousness and presence of seizures.

Introduction: the world is going through a critical situation due to the coronavirus pandemic (COVID-19); this situation causes negative emotional states in people suffering from any respiratory disease or related pathology. Objective: to establish the relationship between emotional state and respiratory diseases in college students at the Universidad Nacional Amazónica de Madre de Dios (UNAMAD), during the COVID-19 pandemic. Method: a descriptive correlational non-experimental research was carried out with the application of a questionnaire composed of 33 items oriented to identify the level of stability, tension or instability in 80 college students of the aforementioned institution during the month of December 2020, using Chi-square, V Cramer and Lambda tests. Results: females (53.8%) and those who were in a degree in Education were predominant. The highest incidence was in the age group 17-19 years (48.8%). Respiratory disease was found in 26.8% (80 students). Regarding the emotional state, 40 % reported living under stress, 36.3% presented a state of emotional stability and 23.8% were in a state of emotional instability. The intensity of relationship between both variables was high. Conclusions: the asymptotic significance between the following dimensions: emotional awareness, emotional control, emotional autonomy and socioemotional skills, is demonstrated by the existence of a relationship, the statistical dependence, between the dimensions of emotional state variables and the variable respiratory diseases.

Introduction: no studies have been conducted to characterize patients with HIV/AIDS infection in Manuel Tames municipality, Guantánamo. Objective: to characterize clinically and epidemiologically the HIV/AIDS infected patients in Manuel Tames municipality, Guantanamo. Method: a descriptive, cross-sectional, retrospective study was carried out, covering the period 1988-2020. The studied population consisted of 46 patients with a diagnosis of HIV/AIDS. Variables studied were as follow: age, sex, marital status, year of the diagnosis report, clinical classification, source of information, scheme of treatment, concomitant diseases. Results: patients 25 to 35 years old were found as the most affected (n=18; 31.9%), with a predominance of males (n=28; 60.9%). Most of patients were found single (n=37; 80.4%). The most common source of information was the capitated category (n=11; 23.9%). Most patients were found in category A (n=33; 71.7%), which supports the figure that 32 patients (69.6%) had no disease associated with virus infection. The highest percentage of patients used the Dulutegravir plus Trubada treatment scheme (n=26; 56.5%). Conclusions: as an end point of the outcome it can be said that HIV/AIDS infection is a disease seen in the middle ages of life, with an increasing number of infections as the years go by. When patients maintain a correct treatment schedule, fewer concomitant diseases are observed and they remain in the clinical categories with the fewest complications.

Introduction: in Cuba, the surveillance and active search for COVID-19 confirming cases and their contacts are actions still performing at the community, and later keep their follow-up at the health care services organized in the national territory. These actions at pediatric ages are a health authorities concern. Objective: to describe the behavior of the main clinical-epidemiological variables of children treated at the "Villa Azucarera" field hospital in Camagüey, from March 4 to April 17, 2021. Methods: a descriptive cross-sectional study was carried out in 287 patients admitted to the hospital with diagnostic criteria of suspected COVID-19 from different health areas in the province. The following variables were analyzed: age, sex, epidemiological criteria, RT-PCR result, clinical criteria and diagnosis at discharge in cases that were negative to the confirmatory test. Results: twenty nine patients of the total (10.1 %) were tested positive for SARS-CoV-2. The contacts of confirmed cases (43.2%) were predominant. Rhinorrhea was the most frequent symptom (13; 44.8%). Common cold (53.9%) and non-specific febrile syndrome (15.1%) were the most frequent diagnoses in negative patients. Conclusions: age and sex do not show significant differences between suspected and confirmed cases. Clinical manifestations are similar in both groups with predominance of fever and high respiratory symptoms, although other digestive and neurological manifestations are described. Close contact with confirmed cases is the main epidemiological factor related to the diagnosis of the disease.

Introduction: professional development embraces several teaching-learning processes that contribute for acquiring and improving in graduated universitary students and workers the required knowledge and skills to succeed in their responsibilities and job functions in different work sectors. Objective: to diagnose current state of the professional development plan given at the Centro Provincial de Información de Ciencias Médicas Guantánamo in order to be implemented via Aula Virtual de Salud. Method: a descriptive and cross-sectional study was conducted at the aforementioned center, during the period 2016 to 2019. The number of activities provided according to the postgraduated development courses, as well as the occupational, teaching and research categories of those who received the training, were quantified. Results: information literacy and article writing programs were marked with the highest number of participants in the last years. Several courses including Information literacy (ALFIN), scientific writing and others, which help professionals in their way to increase they skills as researchers, were conducted. Conclusions: professional population admit the importance of information literacy as it enables them to be updated on any interest subject and to acquire skills for consulting and retrieving information using confidence data sources.

Introduction: illicit drug use is considered a favorable element highly associated to suicidal behavior. As the frequency, intensity, time of consumption and coexistence with other mental disorders, the probability of violent behavior towards oneself also increases. Objective: to characterize drug addict patients with suicidal behavior and determine possible links between sociodemographic and consumption variables. Method: a cross-sectional study in drug addict patients admitted in the Unidad de Conductas Adictivas (UCA) setted at the Instituto de Neurociencias (INC) in Guayaquil, Ecuador, was carried out, in the period 2010 throughout 2016. A total of 922 patients who referred any kind of suicidal behavior (including any kind of suicidal ideation or suicidal intent) were selected. Results: this research revealed that male population was predominant, in which 4 of 10 attempted suicide (36.3%), meanwhile in females was 5 in 10 approximately (46.3%). Conclusions: among patients with suicidal behavior admitted in the Unidad de Conductas Adictivas (UCA) setted at the Instituto de Neurociencias (INC) in Guayaquil, Ecuador, between 2014 and 2017, women who suffered depressive symptoms or had schizophrenia as comorbidity were predominant. Women 15 to 20 years of age and with previous suicidal intent and depressive symptoms.

Introduction: cervical uterine cancer is a malignant neoplasm that is associated with remarkable number of risk factors, including sexual behavior. Objective: to analyze the clinical-epidemiological characteristics of women with altered cytology treated by a basic work group at the Policlínico Docente Comunitario "Joaquín de Agüero y Agüero", in Camagüey municipality. Method: a cross-sectional and descriptive study was conducted from January to December 2020. It worked with a total of 62 women (as universe) treated in 11 different urban clinics associated to the Basic Work Group 1, all women with altered cytology diagnosed by histological and/or cytological study. Variables used were as follow: group of age, family history linked to the cervical and uterine body pathologies, risk factors, human papilloma virus (HPV) infection and histopathological Papanicolaou results. Data processing and analysis were performed using the statistical package SPSS version 21.0. Results: the highest incidence of cervical uterine lesions occurred in the group of age 25 to 34 (43.5%), and the 45.1% showed a maternal family history. Vaginal infection (100%) and multiparity (82.2%) were considered the main risk factors. Patients with HPV predominated in 87.1%. In addition, cytology with findings of cervical intraepithelial neoplasia (CIN 1) was the most frequently diagnosed (40.3%). Conclusions: it is concluded that the risk factors analyzed show a significant direct relationship between HPV and altered cervical cytology outcomes.